About ConXport Rota Rod 4 Comp.
ProductDescription
ROTAROD APPARATUS 4 COMP. DIGI. RPM
ROTAROD is the instrument meant for studying the effect of on the muscle gripstrength of mice.
A versatile built with LSI chips isequipped with Four/ Two/Three compartments and Four/Two/Three independent 4digits. Digital milliseconds timer for measuring the fall-off time of the mice.
It is also equipped with a motorcoupled with rotating rod whose speed can be varied with the help of the frontpanel knob marked with an arrow or speed less than 10 RPM.
One of the important pharmacologicalactions of anti anxiety of agents of class of drugs is muscle relaxingproperty. The skeletal muscle relaxation together with taming or calming effectthese agents reduces anxiety and tension. The loss of muscle-grip is anindication of muscle relaxation; this can be easily checked in animals, usingROTAROD.
The difference in the fall of timefrom the rotating rod between the control and treated animals is taken an indexof muscle relaxation. The rate of rotation of the rod should be adjusted suchthat normal mouse can stay on the rod for an appropriate period of time.
Efficient Assessment of Locomotor CoordinationWith four separate compartments and a non-slip rotating rod, the ConXport Rota Rod enables simultaneous and independent testing of multiple rodents. It provides precise data for evaluating balance, fatigue, and coordination, making it indispensable for neuropharmacological and drug research studies involving laboratory mice and rats.
Flexible and Accurate OperationEquipped with adjustable speeds (540 RPM) and a digital timer display, the Rota Rod offers customizable testing parameters to suit diverse experimental needs. Its semi-automatic operation and high timer accuracy ensure reproducibility and reliability of results while promoting ease of use in laboratory settings.
Robust Design and Safety FeaturesConstructed from durable mild steel with a powder-coated finish and chrome-plated stainless steel rods, the unit ensures longevity and easy maintenance. Safety is prioritized with non-slip grooved rods, individual compartment doors, and stable housing, providing a secure environment for both animals and researchers.
FAQs of ConXport Rota Rod 4 Comp.:
Q: How is the ConXport Rota Rod 4 Comp. used for testing animal locomotor coordination?
A: This device is utilized by placing laboratory mice or rats into one of the four independent compartments, each with a rotating rod. The rotation speed can be set between 5 to 40 RPM, and a digital timer measures the duration each animal remains on the rod. Researchers analyze the fall-off time to evaluate motor coordination, balance, and fatigue.
Q: What makes the ConXport Rota Rod suitable for pharmacological studies?
A: The Rota Rods precise speed control, digital timer (0999 seconds), and capacity to test four animals at once facilitate accurate assessments of neuromotor effects of drugs or treatments. Its reproducibility, combined with secure safety features, supports high-quality, repeatable data collection for pharmacological research.
Q: When should the Rota Rod test be performed in a research setting?
A: This test is typically performed during studies evaluating neurological function, drug efficacy, or fatigue resistance in laboratory rodents. It is particularly valuable when tracking changes in locomotor abilities before and after administration of pharmaceuticals or experimental compounds.
Q: Where can the ConXport Rota Rod 4 Comp. be installed and used?
A: The compact, durable design allows for easy installation in laboratory animal facilities, research institutions, and academic environments. Its electric mains operation and robust build make it well-suited for use in controlled, ambient laboratory conditions.
Q: What is the process for conducting a Rota Rod experiment with this instrument?
A: Start by placing each animal in separate compartments and setting the desired speed and timer. Initiate the rotation; animals will attempt to remain on the non-slip rod. The digital timer records the duration until each animal falls off, providing objective data for locomotor performance assessment.
Q: How does the Rota Rod benefit research involving laboratory mice and rats?
A: It enables quantitative, unbiased measurement of motor coordination and balance. Multiple safety features minimize risks, while digital controls allow for consistent, reproducible results. Researchers can efficiently compare groups and measure the effects of interventions with high confidence.
Q: Which safety and operational features enhance usability of the device?
A: Key features include non-slip, grooved rods to prevent accidental slips, individualized compartment doors to keep animals secure, and a digital LED display ensuring clear readouts. The semi-automatic operation reduces manual handling, and robust construction ensures longevity and reliability.